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thus, specific amino acid deprivation by drugs (e.g., apilimod, DQ661, and bafilomycin A1), which shut down nutrient scavenging pathways (e.g., suppressing lysosomal fusion, acidification, and nutrient export from lysosome), have aroused great interest (Gayle et al., 2017
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However, currently available data indicate that this disinterest in high-calorie products (and overconsumption of food in general) is reversible and that stopping treatment quickly leads to a regain of most of the weight initially lost
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